- immunoglobulin isotype
- иммуноглобулиновый изотип
English-Russian small dictionary of medicine. Г.Ю. Бельман, А.Е. Бойков.. 2015.
English-Russian small dictionary of medicine. Г.Ю. Бельман, А.Е. Бойков.. 2015.
Immunoglobulin E — In biology, Immunoglobulin E (IgE) is a class of antibody (or immunoglobulin isotype ) that has only been found in mammals. It plays an important role in allergy, and is especially associated with type 1 hypersensitivity. [cite journal… … Wikipedia
Isotype (immunology) — In immunology, the immunoglobulin isotype refers to the genetic variations or differences in the constant regions of the heavy and light chains of the Ig (immunoglobulins)classes and sub classes. In humans, there are nine isotypes:* heavy chain… … Wikipedia
isotype switching — The switch of immunoglobulin isotype that occurs, for example, when the immune response progresses (IgM to IgG). The switch from IgM to IgG involves only the constant region of the heavy chains (from m to g ), the light chain and variable regions … Dictionary of molecular biology
immunoglobulin E — noun A class of antibody (or immunoglobulin isotype ) found in mammals. Syn: IgE … Wiktionary
Immunoglobulin G — (IgG) is a monomeric immunoglobulin, built of two heavy chains γ and two light chains. Each IgG has two antigen binding sites. It is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids,… … Wikipedia
Immunoglobulin D — (IgD) is an antibody isotype that makes up about 1% of proteins in the plasma membranes of immature B lymphocytes where it is usually coexpressed with another cell surface antibody called IgM. IgD is also produced in a secreted form that is found … Wikipedia
Immunoglobulin class switching — Mechanism of class switch recombination that allows isotype switching in activated B cells Immunoglobulin class switching (or isotype switching or isotypic commutation or class switch recombination(CSR)) is a biological mechanism that changes a B … Wikipedia
Immunoglobulin — A protein produced by plasma cells and lymphocytes. Immunoglobulins are an essential part of the body s immune system which attach to foreign substances, such as bacteria, and assist in destroying them. Abbreviated Ig. The classes of… … Medical dictionary
Immunoglobulin light chain — Schematic diagram of an typical antibody showing two Ig heavy chains (blue) linked by disulfide bonds to two Ig light chains (green). The constant (C) and variable (V) domains are shown … Wikipedia
isotype — An antigenic determinant (marker) that occurs in all members of a class or subclass in the heavy chains of an immunoglobulin or in the type and subtype of light chains of an immunoglobulin molecule. Whereas a given allotypic … Medical dictionary
isotype — (1) Applied to a set of macromolecules sharing some features in common. In immunology isotype describes the class, subclass, light chain type and subtype of an immunoglobulin. (2) Antigenic determinant that is uniquely present in individuals of a … Dictionary of molecular biology